Autosomal dominant deafness accounts for about 15% of hereditary deafness.Contrary to recessive hereditary deafness, dominant hereditary deafness is characterized by the fact that as long as the patient carries a single dominant gene mutation, it can cause deafness. One of the patient’s parents and older ancestors often has deaf patients, and the family history is more obvious.Most deafness with dominant inheritance has mild hearing loss. Hearing conditions are usually acceptable at birth, but gradually deteriorate with age in later stages.
The ratio of sex-linked chromosome inheritance and mitochondrial maternal inheritance is relatively low, accounting for only 2-3% of hereditary deafness.However, compared with other countries and races, the mitochondrial gene mutation A1555G is relatively more common in the Chinese population.This mutation can cause patients to be sensitive to aminoglycoside antibiotics, which can easily lead to drug-induced deafness.Therefore, people with mutations in the mitochondrial gene A1555G should try to avoid exposure to aminoglycoside antibiotics such as gentamicin and streptomycin. This is especially true for newborns who are more susceptible to infections and often need to use antibiotics. important.